| N-terminal Modification | | {H-},Free amino group | | {Ac},Acetylation | | {Br-Ac},Bromoacetyl | | {Bromopropionyl} | | {Cl-Ac},Chloroacetyl | | {Fmoc},9-Fluorenylmethyloxycarbonyl | | {Z},{CBZ},Benzyloxycarbonyl | | {Bz},benzoyl | | {4-F-Bz} | | {Cl-Ac},Chloroacetyl | | {Boc},tertbutoxycarbonyl | | {Suc},succinyl | | {MeO-Suc} | | Sebacic acid | | {Allyl},allyl | | {Acryl},acryl | | {Alloc},allyloxycarbonyl | | {For}, Formylation | | {HPP},4-Hydroxyphenylpropionic acid | | {pGlu},{Pyr},Pyroglutamyl | | {LA}, Lipoic acid | | {Mpa},3-Mercaptopropyl | | {6-mercaptohexanoic acid} | | {Mal}, Maleimide, Maleoyl-b-Ala | | Mal-Acp | | {MTX}, Methotrexate | | {PEG1900}, PEG1900-NH- | | {NH2-PEG2000}, NH2-PEG2000-NH-Suc- | | {mPEG2000}, MeO-PEG2000-NH- | | {mPEG3000}, MeO-PEG3000-NH- | | {mPEG5000}, MeO-PEG5000-NH- | | {SATA}, S-acetylthioacetate | | {SATP}, S-acetylthiopropionate | | {Cholesteryl-}, Cholesteryl chloroformate | | {Glucose-} | | {Fructose-} | | Pyridin-1-yl-Acetyl- | | 4-Dimethylamino-Pyridin-1-yl- | | Adamantanecarbonyl- | | Phenylacetic acid | | 4-Biphenyl sulfonyl- | | Nitrilotriacetyl- | | N-Propargylglycine- | | HYNIC- | | Morpholine-4-carbonyl- | | 5-amino-2-nitrobenzonic acid | | Azido-PEG4- | | GAC- | | {Aoa} | | N3-Gly | | N3-Acp |
| | Fluorescence/Dye Labeling | | Biotin (N-Terminal) | | EDBiotin (C terminus) | | Lys(Biotin) (middle) | | Lys(Biotin) (C temrinus) | | Lys(Biotin) (N terminus) | | Biotin-LC (N-Terminal) | | Lys(LC-Biotin) (middle) | | Lys(LC-Biotin) (C terminus) | | Orn(Bio) | | -NH-PEG3-Bio | | FITC (N-Terminal) | | EDFITC (C temrinus) | | Lys(FITC) (middle) | | Lys(FITC) (C temrinus) | | Lys(FITC) (N terminus) | | FITC-LC (N-Terminal) | | 5-FAM (N-Terminal) | | ED5-FAM (C temrinus) | | Lys(5-FAM) (middle) | | Lys(5,6-FAM) | | Lys(5-FAM) (C temrinus) | | Lys(5-FAM) (N-Terminus) | | 5-FAM-LC (N-Terminal) | | Dansyl (N-Terminal) | | EDDansyl (C temrinus) | | Lys(Dansyl) (middle) | | Lys(Dansyl) (C temrinus) | | Lys(Dansyl) (N-Terminus) | | Dansyl-LC (N-Terminal) | | TAMRA (N-Terminal) | | 5(6)-TAMTA- | | EDTAMRA (C temrinus) | | Lys(TAMRA) (middle) | | Lys(TAMRA) (C temrinus) | | Lys(TAMRA) (N-terminus) | | TAMRA-LC (N-Terminal) | | Lys(Dnp) (middle) | | D-Lys(Dnp) (middle) | | Dab(Dnp) (middle) | | Dap(Dnp) (middle) | | EDDnp (C terminus) | | MCA (N-Terminal) | | Lys(MCA) (middle) | | Lys(MCA) (C temrinus) | | Lys(MCA) (N-terminus) | | 3-Indolylacetic acid (N-Terminal) | | Cys(Npys) (N-terminus) | | PyBA- (N-Terminal), 1-pyrenebutyric acid | | Lys(PyBA) | | Fa- (N-Terminal), 3-[2-2furyl]acrylic | | acid | | Rhodamine B- (N-Terminal) | | D-Luciferin (N-terminus) | | Cy3- (N-Terminal) | | NBD |
| | Phe/Tyr Analog Amino Acids | | {D-2-Cl-Phe} | | {L-2-Cl-Phe} | | {D-3-Cl-Phe} | | {L-3-Cl-Phe} | | {D-4-Cl-Phe} | | {L-4-Cl-Phe} | | {D-3,4-DiCl-Phe} | | {L-3,4-DiCl-Phe} | | {D-4-Br-Phe} | | {L-4-Br-Phe} | | {D-3-F-Phe} | | {L-3-F-Phe} | | {D-4-F-Phe} | | {L-4-F-Phe} | | {D-4-NO2-Phe} | | {L-4-NO2-Phe} | | {D-4-I-Phe} | | {L-4-I-Phe} | | {D-3-CN-Phe} | | {L-3-CN-Phe} | | {D-4-CN-Phe} | | {L-4-CN-Phe} | | {D-2-Me-Phe} | | {L-2-Me-Phe} | | {D-4-Me-Phe} | | {L-4-Me-Phe} | | {D-4-NH2-Phe} | | {L-4-NH2-Phe} | | {D-3-Cl-Tyr} | | {L-3-Cl-Tyr} | | {D-3,5-DiCl-Tyr} | | {L-3,5-DiCl-Tyr} | | {D-3,5-DiBr-Tyr} | | {L-3,5-DiBr-Tyr} | | {D-3-I-Tyr} | | {L-3-I-Tyr} | | {D-3,5-DiI-Tyr} | | {L-3,5-DiI-Tyr} | | {D-3-NO2-Tyr} | | {L-3-NO2-Tyr} | | {D-3,5-DiNO2-Tyr} | | {L-3,5-DiNO2-Tyr} | | {L-3-F-Tyr} |
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| N-Terminal FATylation | | {But}, Butyric acid C4 | | {Iba}, isobutyric acid C4 | | {Hex}, Hexanoic acid C6 | | {Oct}, Octanoic acid C8 | | {F-Oct}, Perfluoro Octanoic acid F15C8 | | {Dec}, Decanoic acid C10 | | {F-Dec}, Perfluoro Decanoic acid F19C10 | | {Lau}, Lauric acid C12 | | {F-Lau}, Perfluoro Lauric acid F23C12 | | {Myr}, Myristic acid C14 | | {F-Myr}, Perfluoro Myristic acid F27C14 | | {Pal}, Palmitic acid C16 | | {Ste}, Stearic acid C18 | | {Ste}, Stearic acid C18 | | Oleic Acid- | | {Pam3C}, Tripalmitoyl cysteine, {Pal-Cys(Pal)2-} |
| Quenched Fluorescent Peptides | | Abz | | Tyr (3-NO2) | | Glu(EDANS)-NH2 | | DABCYL | | Lys(DABCYL) | | Lys(Abz) |
| | C-Terminal Modification | | {-OH}, free acid group | | {NH2}, Amidation | | {-CHO}, peptide aldehydes | | {-ol}, alcohol peptide | | {CMK}, chloromethylketone | | {FMK}, Fluoromethylketone | | {Cya}, Cysteamide | | {pNA},p-nitroaniline | | {-ONP}, para-nitrophenol | | {AMC},7-Amino-4-methylcoumarin | | {AFC} | | -OMe (C-terminal) | | -OEt (C-terminal) | | -OBzl (C-terminal) | | -OtBu (C-terminal) | | {-OSu}, hydroxysucinimide ester | | -NHMe (C-terminal) | | -NHEt (C-terminal) | | -NHisopen (C-terminal) | | -NH(CH2)6 (C-terminal) | | -NHPh (C-terminal) | | {NHEt(O)EtNH-Fmoc}, 2,2'-Oxydi Ethanamine-Fmoc | | {NHEt(EtNH-Myr)2} | | -NH(OMe)Me (C-terminal) | | -TBzl (C-terminal) | | -NHNH2 (C-terminal) | | -ED (C-terminal), -NH-CH2CH2-NH2 | | -BD (C-terminal), -NH-CH2CH2CH2CH2-NH2 | | -Pyrenemethylamine | | chloro-4-hydroxyanilide | | 4-amino-2-Chlorophenol | | -octyl ester | | -ED-Fmoc |
| | D-amino Acids | | {D-Ala} | | {D-Arg} | | {D-Asp} | | {D-Asn} | | {D-Cys} | | {D-Glu} | | {D-Gln} | | {D-His} | | {D-Allo-Ile} | | {D-Leu} | | {D-Lys} | | {D-Met} | | {D-Pro} | | {D-Phe} | | {D-Ser} | | {D-Tyr} | | {D-Thr} | | {D-Trp} | | {D-Val} |
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| Homo-Amino Acids | | {Har}, HomoArg | | {Hcy}, HomoCys | | {HPh}, HomoPhe | | {D-HPh}, D-HomoPhe | | {Hse}, HomoSer | | {D-Hse}, D-HomoSer | | {HomoCit}, HomoCit | | {D-HomoCit}, D-HomoCit | | {HomoLeu}, HomoLeu | | {HomoPro}, HomoPro | | {D-HomoPro}, D-HomoPro | | {beta-HomoIle}, beta-HomoIle | | {beta-HomoLeu}, beta-HomoLeu | | {beta-HomoMet}, beta-HomoMet | | {beta-HomoPro}, beta-HomoPro | | {beta-HomoVal}, beta-HomoVal | | {beta-HomoAsp}, beta-HomoAsp | | {beta-HomoAsn}, beta-HomoAsn | | {beta-HomoGlu}, beta-HomoGlu | | {beta-HomoGln}, beta-HomoGln | | {beta-HomoSer}, beta-HomoSer | | {beta-HomoThr}, beta-HomoThr | | {beta-HomoTrp}, beta-HomoTrp | | {beta-HomoTyr}, beta-HomoTyr | | {Azidohomoalanine}, Azidohomoalanine | | {beta-HomoAla}, beta-HomoAla | | {beta-HomoPhe}, beta-HomoPhe | | {beta-HomoLys}, beta-HomoLys |
| Atom Linkers | | {Gly}, 2 atoms | | {Beta-Ala}, 3 atoms | | {GABA}, 4 atoms | | {Ava}, 5 atoms | | {Ahx}, 6 atoms | | {8-Aoc} | | {AEA},aminoethoxyacetic acid | | {Mini-PEG}, AEEA 9 atoms | | {Mini-PEG2}, AEEEP 13 atoms | | {Mini-PEG3},AEEEEP 16 atoms | | {PEG4} | | {PEG6} | | {PEG8} | | {PEG11} | | {PEG-12} | | {Ado} | | {ANP Linker} |
| Cyclic Peptides | | Mono Disulfide bridge | | Double Disulfide bridge | | Triple Disulfide bridge | | Random Triple Disulfide bridge | | Same Seq. Inter-Disulfide bridge | | Different Inter-Disulfide bridge | | Amide cyclic (end) | | Amide cyclic (Side chain) | | Orn side chain Amide cyclic | | Thioester cyclic | | Lactone cyclic |
| N-Methyl Amino Acids | | {N-Me-Ala} | | {N-Me-Phe} | | {N-Me-Leu} | | {N-Me-Ile} | | {N-Me-Val} | | {N-Me-Met} | | {N-Me-Nle} | | {N-Me-Nva} | | {N-Me-Gly}, Sar | | {N-Me-Ser} | | {N-Me-Tyr} | | {N-Me-Thr} | | {N-Me-Asp} | | {N-Me-Glu} |
| | Unnatural/Unusual amino acids | | {Beta-Asp} | | {D-Beta-Asp} | | {Gamma-Glu} | | {D-Gamma-Glu} | | {Cys(Cam)} | | {Cys(Acm)} | | {Cys(tBu)} | | {Met(O)} | | {D-Met(O)} | | {Met(O)2} | | {D-Met(O)2} | | {Lys(Ac)} | | {Ac-Lys} | | {Lys(Dde)} | | {Tle} | | {Ser(octanoic acid)} | | {D-Ser(octanoic acid)} | | {Aib} | | {Abu} | | {D-Abu} | | {Hyp} | | {Phg} | | {D-Phg} | | {Nva} | | {D-Nva} | | {Nle} | | {D-Nle} | | {Cit} | | {D-Cit} | | {Orn} | | {D-Orn} | | {Pen} | | {D-Pen} | | {Cpg}, cyclopentylglycine | | {Cha} | | {D-Cha} | | {Chg} | | {D-Chg} | | {Dab} | | {Dap} | | {Pra} | | {D-Pra} | | {Gly(allyl)} | | {D-Gly(allyl)} | | {D-1-Nal} | | {L-1-Nal} | | {D-2-Nal} | | {L-2-Nal} | | {D-2-Pal} | | {L-2-Pal} | | {D-3-Pal} | | {L-3-Pal} | | {D-4-Pal} | | {L-4-Pal} | | {Cys(pMeBzl)} | | {Cys(pMeOBzl)} | | {Oic} | | {Tic} | | {Cys(Bzl)} | | {Epsilon-Lys} | | {D-Epsilon-Lys} | | {5-ASA} | | {Bpa} | | {Pip} | | {Nip} | | {2-Aze} | | {3-Aze} | | [Psi(CH2NH)] | | [CS-NH] | | {Se-Met} | | {Se-Cys} | | {DOPA} | | {isoGln} | | {D-isoGln} | | Cys(Mal-PEG2000) | | {Ser(O-b-D-Glc)} | | {Thr(O-b-D-Glc)} | | {Tyr(O-b-D-Glc)} | | {Rink Linker} | | {Thr(OAc)} | | {Delta-Orn} | | {5,5-Dime-Pro} | | {Gla} | | {Kep} | | {X}, 20 Kinds mixture amino acids | | {X-deCys} | | {G/A/S/V/L/D/K/M/F/Y} | | {A/P/T/N/Q/E/H/R/W} | | {K(75)X(25)} | | {R(25)K(25)X(50)} | | {E(25)D(25)X(50)} | | {K(25)Q(25)X(50)} | | {E(25)T(25)X(50)} |
| | MAPS and Carrier Complexes | | Symmetric 2 Branches (Pure) | | Orn Symmetric 2 Branches (Pure) | | Symmetric 4 Branches (Crude) | | Orn Symmetric 4 Branches (Crude) | | Symmetric 8 Branches (Crude) | | Orn Symmetric 8 Branches (Crude) | | Glu 2 Branches (N temrinus) | | Glycerol 3 branches (C terminus) | | Lys(Ala) | | Lys(Arg) | | Lys(Asp) | | Lys(Cys) | | Lys(Glu) | | Lys(Leu) | | Lys(Met)- | | Lys(Phe)- | | Lys(Val) | | Lys(Beta-Asp) | | Lys(Gama-Glu) | | Lys(Cholesteryl) | | Lys(LA) | | Lys(MTX) | | Lys(Maleimide) | | Lys(Mpa) | | Lys(Pra) | | Lys(Suc) | | Lys(pGlu) | | Lys(For) | | Lys(Ma) | | Lys(Pal) | | Lys(Gama-Glu-Pal) | | Lys(4-HBA) | | Lys(Acrylic) | | Lys(Alkine) | | {Lys(Alloc)} | | {Lys(Butanoyl)} | | Lys(cyclopropanecarboxyl) | | Lys(Crotonyl) | | {Lys(3,5-diiodo-4-hydroxybenzoyl)} | | Lys(HMP) | | {Lys(Ahx-Diazirine)} | | {Lys(propargyl)} | | {Lys(propionyl)} | | Lys(2-hydroxyisobutyryl) | | Lys(methylmalony) | | Lys(HYNIC) | | BSA-Peptide Cys | | KLH-Peptide Cys | | OVA-Peptide Cys |
| Methyl Amino Acids | | {Arg(Me)} | | {ADMA},{Arg(Me)2} asymmetrical | | {SDMA},{Arg(Me)2} symmetrical | | {Tyr(Me)} | | {Thr(Me)} | | {Ser(Me)} | | {Cys(Me)}, SMC | | {Lys(Me)} | | {Lys(Me2)} | | {Lys(Me3)} | | {L-2-Me-Trp} | | {D-2-Me-Trp} | | {Tyr(Et)} | | {D-Tyr(Et)} | | {Orn(Me)3} | | {L-1-Me-Trp} |
| Phosphorylation | | {pSer} | | {pTyr} | | {pThr} | | {D-pSer} | | {D-pTyr} | | {D-pThr} | | Di-sites in sequence | | Tri-sites in sequence | | 4-sites in sequence | | 5-sites in sequence |
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