IL8, Human (77 a.a.)

PRODUCT DESCRIPTION
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Interleukin-8, 77 a.a.
HuIL8
Chemokin, CXC Motif, Ligand 8 (CXCL8)
Monocyte-Derived Neutrophil Chemotactic Factor
Small Inducible Cytokine Subfamily B, Member (SCYB8)

Interleukin-8 (IL8) is encoded by the IL8 gene and produced by macrophages and other cell types such as epithelial cells. There are many receptors capable of binding to IL8; however, the molecules with the highest affinity to IL8 are receptors CXCR1 and CXCR2. As a member of the CXC chemokine family, one of the functions of IL8 is the induction of chemotaxis in its target cells, like neutrophil granulocytes, basophils and T-cells. IL8 (72a.a.) has a 5-10-fold higher activity on neutrophil activation, compared to IL8 (77 a.a.). IL8 is often associated with inflammation, and has been cited as a pro-inflammatory mediator in gingivitis and psoriasis.

Sterile Filtered White Lyophilized Powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~8.9 kDa (77 amino acids)

Purity: >96% by SDS-PAGE and HPLC analyses.

Storage/Handling: Store desiccated at -20°C.

NOT FOR HUMAN USE!

HGNC: 6025

Additional resources for this protein may be found at: OMIM