PRODUCT DESCRIPTION
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Recombinant Murine Interleukin-6
IL6
Interferon, Beta-2 (IFNB2)
B-cell Stimulatory factor 2 (BSF2)
Hybridoma Growth Factor (HGF)
Interleukin-6 (IL6) is a multifunctional protein that plays an important role in host defense, acute phase reactions, immune responses and hematopoiesis. IL6 is expressed by a variety of normal and transformed cells including T-cells, B-cells, monocytes/macrophages, fibroblasts, hepatocytes, keratinocytes, astrocytes, vascular endothelial cells and various tumor cells. The production of IL6 is upregulated by numerous signals, including mitogenic or antigenic stimulation, LPS, calcium ionophore, IL1, IL2, IFN, TNF, PDGF, and viruses. IL6 expression in monocytes is inhibited by IL4 and IL13.
Sterile Filtered White Lyophilized Powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~21.7 kDa (187 amino acids)
Purity: >97% by SDS-PAGE and HPLC analyses.
Storage/Handling: Store desiccated at -20°C.
NOT FOR HUMAN USE!
MGI: 96559
Cross-species Homology
Percent Similarity:
| | HuIL6 | MuIL6 | RtIL6 |
| HuIL6 | *** | 40.4 | 39.9 |
| MuIL6 | *** | *** | 85.0 |
| RtIL6 | *** | *** | *** |
Additional resources for this protein may be found at: OMIM
