SKU : cyt-978
Recombinant Human CD4 (26-396), Sf9
หมวดหมู่ : Prospec , 
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SYNONYMS
CD4 Molecule, T-Cell Surface Antigen T4/Leu-3, CD4 Antigen (P55), T-Cell Surface Glycoprotein CD4, CD4 Receptor, CD4 Antigen, CD4mut.
INTRODUCTION
CD4 is a cell-surface glycoprotein found on the mature helper T cells and immature thymocytes, as well as on monocytes and macrophages. (Some cytotoxic T cells have CD4 protein as well.) Normally, about 65% of T cells in the blood are CD4+ (have CD4 protein protruding from their membrane). A mature T cell with either have CD4 or CD8, but not both. During one stage of development T cells develop CD4 and CD8 receptors, but they eventually are differentiated in the thymus and become more specialized.
DESCRIPTION
CD4 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 377 amino acids (26-396a.a.) and having a molecular mass of 42.1kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).
CD4 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.