PRODUCT DESCRIPTION
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Recombinant Murine Interleukin-11
IL11
Interleukin 11
Megakaryocyte Colony Stimulating Factor (Meg-CSF)
Interleukin-11 (IL11) is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL1α-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL6-responsive murine plasmacytoma cell line T11. IL11 contains no cysteine residues or potential glycosylation sites. IL11 has multiple effects on both hematopoietic and nonhematopoietic cells. Many of the biological effects described for IL11 overlap with those of IL6. In vitro, IL11 can synergize with IL3, IL4 and SCF to shorten the G0 period of early hematopoietic progenitors. IL11 also enhances the IL3-dependent megakaryocyte colony formation. IL11 has been found to stimulate the T-cell dependent development of specific immunoglobulin-secreting B-cells.
Sterile Filtered White Lyophilized Powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~19.1 kDa (179 amino acids)
Purity: >97% by SDS-PAGE and HPLC analyses.
Storage/Handling: Store desiccated at -20°C.
NOT FOR HUMAN USE!
MGI: 107613
Cross-species Homology
Percent Similarity:
| | HuIL11 | MuIL11 |
| HuIL11 | *** | 87.7 |
| MuIL11 | *** | *** |
Additional resources for this protein may be found at: OMIM
