SYNONYMS
GP52-40, TSPAN26, Leukocyte antigen CD37, Tetraspanin-26, Tspan-26.
INTRODUCTION
CD37 belongs to the transmembrane 4 superfamily, otherwise known as the tetraspanin family. Most of its members are cell-surface proteins which are distinguished by the presence of 4 hydrophobic domains. These proteins mediate signal transduction events which have a role in the regulation of cell development, activation, growth and motility. CD37 protein is a cell surface glycoprotein which is known to form complexes with integrins and other transmembrane 4 superfamily proteins. CD37 may also havea role in T-cell-B-cell interactions.
DESCRIPTION
CD37 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 154 amino acids (112-241 a.a) and having a molecular mass of 17.4kDa.
CD37 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
