SYNONYMS
CD44 Molecule (Indian Blood Group), Hematopoietic Cell E- And L-Selectin Ligand, GP90 Lymphocyte Homing/Adhesion Receptor, Chondroitin Sulfate Proteoglycan 8, Extracellular Matrix Receptor III, Heparan Sulfate Proteoglycan, Phagocytic Glycoprotein 1, Hyaluronate Receptor, Hermes Antigen, ECMR-III, HUTCH-I, Epican, CDW44, MDU2, MDU3, MIC4, LHR, CD44 Antigen (Homing Function And Indian Blood Group System),Homing Function And Indian Blood Group System, Cell Surface Glycoprotein CD44, Phagocytic Glycoprotein I, Soluble CD44, CSPG8, HCELL, PGP-1, PGP-I, MC56, Pgp1, IN, CD44 .
INTRODUCTION
CD44 is a cell-surface glycoprotein that plays a role in cell-cell interactions, cell adhesion and migration. CD44 is a receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. CD44 participates in a wide variety of cellular functions such as lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis.
DESCRIPTION
CD44 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (21-220 a.a.) and fused to a 239 aa hIgG-His-tag at C-terminus containing a total of 439 amino acids and having a molecular mass of 49kDa.
CD44 shows multiple bands between 57-70kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.
