SKU : pro-1057
Recombinant Human Chromobox Homolog 3
หมวดหมู่ : Prospec ,
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SYNONYMS
Chromobox homolog 3 (Drosophila HP1 gamma), Heterochromatin protein 1 homolog gamma, Modifier 2 protein, HP1 gamma homolog, HECH, HP1Hs-gamma.
INTRODUCTION
CBX3 takes part in transcriptional silencing in heterochromatin-like complexes. CBX3 identifies and binds histone H3 tails methylated at 'Lys-9', thereby create an epigenetic repression. Additionally, CBX3 takes part in the formation of functional kinetochore by interacting with MIS12 complex proteins.
DESCRIPTION
CBX3 Human Recombinant produced in E. coli is a single polypeptide chain containing 207 amino acids (1-183) and having a molecular mass of 23.4kDa.
CBX3 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
