SKU : pro-232
Recombinant Human ADP-Ribosylation Factor-Like 6
หมวดหมู่ : Prospec , 
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SYNONYMS
ADP-ribosylation factor-like 6, Bardet-Biedl syndrome 3 protein, BBS3, RP55, MGC32934.
INTRODUCTION
ARL6 is a member of the ARF family of GTP-binding proteins. ARL6 has a vital part in modulating membrane trafficking and cytoskeletal functions. Mutation in ARL6 is the source of Bardet-Biedl syndrome (BBS3) which is a pleiotropic genetic disorder that causes obesity, photoreceptor degeneration, polydactyly, hypogenitalism, renal abnor-malities and developmental delay.
DESCRIPTION
ARL6 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 206 amino acids (1-186a.a) and having a molecular mass of 23.2kDa.
ARL6 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.