SKU : pro-245
Recombinant Human ADP-Ribosylation Factor 5
หมวดหมู่ : Prospec , 
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SYNONYMS
ADP-ribosylation factor 5, ARF5.
INTRODUCTION
ADP-ribosylation factor 5 (ARF5) is a small guanine nucleotide-binding protein which enhances the enzymatic activities of cholera toxin. ARF-dependent regulatory mechanisms include the coordination of spectrin interactions with golgi membranes and the connection of actin to the golgi via rho family-dependent G-protein localization and WASP/Arp2/3 complexes. ARF5 is involved in vesicular transport and functioning via phospholipase D activation.
DESCRIPTION
ARF5 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 200 amino acids (1-180 a.a) and having a molecular mass of 22.6kDa.
ARF5 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.