SYNONYMS
Annexin A7, Annexin-7, Annexin VII, Synexin, ANXA7, ANX7, SNX.
INTRODUCTION
Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins. Annexin VII has molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.
DESCRIPTION
ANXA7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 490 amino acids (1-466 a.a.) and having a molecular mass of 52.9kDa.
ANXA7 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
