SKU : pka-053
Recombinant Human Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, Beta
หมวดหมู่ : Prospec , 
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SYNONYMS
PI5P4KB, PIP5K2B, PIP5KIIB, PIP5KIIbeta, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta, 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta, Diphosphoinositide kinase 2-beta, Phosphatidylinositol 5-phosphate 4-kinase type II beta, PI(5)P 4-kinase type II beta, PIP4KII-beta, PtdIns(5)P-4-kinase isoform 2-beta, PIP4K2B.
INTRODUCTION
Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, Beta (PIP4K2B) belongs to the phosphatidylinositol-4-phosphate 5-kinase family.PIP4K2B catalyzes the phosphorylation of phosphatidylinositol-4-phosphate on the 5th hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosphate. PIP4K2B amino acid sequence does not show resemblance to another kinases although PIP4K2B presents kinase activity.PIP4K2B also interacts with p55 TNF receptor.
DESCRIPTION
PIP4K2B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 439 amino acids (1-416 a.a) and having a molecular mass of 49.8kDa.PIP4K2B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.