SYNONYMS
Sulfite Oxidase, EC 1.8.3.1, Sulfite oxidase, mitochondrial.
INTRODUCTION
Sulfite oxidase, also known as SUOX is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit includes a heme domain as well as a molybdopterin-binding domain. The SUOX enzyme catalyzes the oxidation of sulfite to sulfate, the last reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. In addition, the deficiency of SUOX results in neurological abnormalities which are often fatal at an early age.
DESCRIPTION
SUOX Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 489 amino acids (80-545 a.a) and having a molecular mass of 53.9kDa.SUOX is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
