PTPRC

SYNONYMS
LCA, LY5, B220, CD45, T200, GP180, Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, L-CA, PTPRC.

INTRODUCTION
Protein Tyrosine Phosphatase Receptor Type C, also known as PTPRC, which is a vital regulator of T- and B-cell antigen receptor signaling, is also a part of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules which regulate a variety of cellular processes including differentiation, cell growth, mitosis, and oncogenic transformation. PTPRC contains an extracellular domain, a single transmembrane segment and 2 tandem intracytoplasmic catalytic domains, and therefore is classified as a receptor type PTP.

DESCRIPTION
PTPRC Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 257 amino acids (1031-1251a.a) and having a molecular mass of 29.6kDa.
PTPRC is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

https://www.prospecbio.com/ptprc_human