SKU : enz-139
Recombinant Human Phosphopantothenoylcysteine Synthetase
หมวดหมู่ : Prospec ,
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SYNONYMS
Phosphopantothenate--cysteine ligase, Phosphopantothenoylcysteine synthetase, PPC synthetase, PPCS, COAB, RP11-163G10.1.
INTRODUCTION
Phosphopantothenate-cysteine ligase (PPCS) catalyzes the first step in the biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5), which is a vital universal pathway in prokaryotes and eukaryotes. PPCS, being one of the last enzymes in this pathway, converts phosphopantothenate to phosphopantothenoylcysteine.
DESCRIPTION
PPCS produced in E.Coli is a single, non-glycosylated polypeptide chain containing 331 amino acids (1-311 a.a.) and having a molecular mass of 36.1kDa.
PPCS is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques
