SKU : enz-181
Recombinant Human Ornithine Decarboxylase 1
หมวดหมู่ : Prospec ,
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SYNONYMS
ODC, Ornithine decarboxylase 1, EC 4.1.1.17.
INTRODUCTION
Ornithine decarboxylase is the preliminary and rate-limiting enzyme in the biosynthetic pathway of polyamines and it takes part in the alteration of ornithine to putrescine. ODC1 is a key member of various biological processes, such as cell growth, transformation, differentiation and apoptosis. Overexpression of the ODC1 gene has a vital part in cell proliferation and the progress of cancer.
DESCRIPTION
ODC1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 484 amino acids (1-461) and having a molecular mass of 53.5 kDa.
ODC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
