SKU : enz-589
Recombinant E.Coli Formamidopyrimidine-DNA Glycosylase
หมวดหมู่ : Prospec ,
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SYNONYMS
Formamidopyrimidine-DNA glycosylase, FPG.
INTRODUCTION
MUTM is a base excision repair enzyme that identifies and eliminates a large variety of oxidized purines from correspondingly impaired DNA. MUTM is nondismissable and essential to remove quickly its substrate lesions on the chromosome. MUTM, additionally, mends a large number of the lesions recognized by Endo III, signifying that MUTM takes a prominent part in the overall repair of both purine damage and pyrimidine damage in vivo.
DESCRIPTION
MUTM Recombinant produced in E. coli is a single polypeptide chain containing 289 amino acids (1-269) and having a molecular mass of 32.4kDa.
MUTM is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
