SYNONYMS
E. coli serine protease inhibitor.
INTRODUCTION
Ecotin inhibits pancreatic serine proteases. Ecotin protein inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases. The power of inhibition is not linked to a specific protease specificity.
DESCRIPTION
Ecotin produced in E.Coli is a single, non-glycosylated polypeptide chain containing 163 amino acids (21-162a.a.) and having a molecular mass of 18.3kDa.
Ecotin is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
