SKU : enz-215
Recombinant Human 3-Hydroxybutyrate Dehydrogenase, Type 1
หมวดหมู่ : Prospec , 
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SYNONYMS
D-beta-hydroxybutyrate dehydrogenase, mitochondrial, BDH, 3-hydroxybutyrate dehydrogenase, BDH1, SDR9C1.
INTRODUCTION
BDH1 belongs to the short-chain dehydrogenase/reductase gene family. BDH1 forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific necessity for phosphatidylcholine for optimal enzymatic activity. BDH1 catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the 2 main ketone bodies formed during fatty acid catabolism.
DESCRIPTION
BDH1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 318 amino acids (47-343) and having a molecular mass of 35.3kDa.
BDH1 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.