SKU : cyt-881
Recombinant Human Brain-Derived Neurotrophic Factor, His Tag
หมวดหมู่ : Prospec , 
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INTRODUCTION
BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. BDNF is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the cns. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (ltp), long-term depression (ltd), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
DESCRIPTION
BDNF Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 140 amino acids (129-247 a.a) and having a molecular mass of 15.8kDa.BDNF is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.