SKU : pka-320
Recombinant Human Glycogen synthase kinase-3 beta
Categories : Prospec ,
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SYNONYMS
GSK3B, Glycogen synthase kinase-3 beta, GSK-3 beta.
INTRODUCTION
GSK3B is a serine-threonine kinase that belongs to the glycogen synthase kinase subfamily. GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in the GSK3B gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of the GSK3B gene may be significant to the pathogenesis of Alzheimer disease.
DESCRIPTION
GSK3B Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 420 amino acids (1-420) and having a molecular mass of 46.0 kDa.
