SKU : cyt-1146
Recombinant Mouse Soluble RANK Ligand (158-316 a.a), Active
Categories : Prospec ,
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SYNONYMS
Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor,
ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE, CD254, Tnfsf11, Opgl, Rankl, Trance
INTRODUCTION
Soluble RANK Ligand or type II membrane protein, is part of the TNF proteins family. RANKL has been found to have an effect on the immune system and regulates bone regeneration and remodeling. This protein regulates cell apoptosis, bunds to OPG protein (osteoprotegerin), cell proliferation regulator and acts as a ligand for RANK receptor. The protein is found to be expressed in various tissues such as thymus, colon, liver, skeletal muscle, osteoblast etc.
DESCRIPTION
sRANKL Mouse produced in E.Coli is a single, non-glycosylated polypeptide chain containing 160 amino acids (158-316a.a) and having a molecular mass of 17.9 kDa.
sRANKL is purified by proprietary chromatographic techniques.
