Adenine 9-ß-D-arabinofuranoside (Vidarabine)
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Categories : 1. Chemical and Reagents , Gold Biotechnology (USA) ,
Brand : Gold Biotechnology (USA)
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PRODUCT DESCRIPTION
Adenine 9-beta-D-arabinofuranoside (ara-A) is a synthetically produced purine nucleoside that is used in cell signaling research. It has commonly been used in anti-viral research with hepadnaviridae and herpes simplex viruses. The nucleoside ara-A interferes with viral DNA synthesis, but only in its active phosphorylated form. Active ara-ATP inhibits synthesis by incorporating into viral DNA and preventing phosphodiester bridge formation.
The compound ara-A is a precursor of adenine 9-beta-D-arabinofuranoside 5’monophosphate (ara-AMP). In vivo rat experiments of ara-AMP have shown a higher solubility and affinity for some proteins, both of which facilitate ara-AMP movement. Isolated human hepatocytes have also been shown to specifically endocytose the albumin/ara-AMP conjugate.
Product Specifications
Adenine 9-beta-D-arabinofuranoside
Vidarabine
Formula: C10H13N5O4
MW: 267.24 g/mol
Storage/Handling: Store at -20°C.
PubChem Chemical ID: 21704
Product Specifications
| Catalog ID | A-145 |
|---|---|
| CAS # | 5536-17-4 |
| MW | 267.24 g/mol |
https://www.goldbio.com/product/13166/adenine-9-beta-d-arabinofuranoside-vidarabine
