TYPE
Mouse Antibody Monoclonal.
INTRODUCTION
p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
CLONE
PP53SHG.
DESCRIPTION
Monoclonal antibodies are produced by immunizing mouse with full length His-tagged p53 protein.
IG SUBCLASS
Mouse IgG2a.
PHYSICAL APPEARANCE
Sterile Filtered solution.
FORMULATION
1×PBS & 50% glycerol.
TITER
Western Blotting: 2μg/ml.
SAFETY DATA SHEET
SDS
APPLICATIONS
Western Blot, Immunoprecipitation.
USAGE
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
