SYNONYMS
Complement decay-accelerating factor, GPI-anchored, DAF-GPI, CD_antigen: CD55.
INTRODUCTION
CD55 belongs to the RCA (regulators of complement activation) family characterized by 4-30 SCRs (short consensus repeats) in their plasma-exposed regions. CD55 is widely expressed in malignant tumors and nevertheless functions as an inhibitor of the complement system.
DESCRIPTION
CD55 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 336 amino acids (35-362 a.a.) and having a molecular mass of 36.8kDa (Migrates at 40-57kDa on SDS-PAGE under reducing conditions).
CD55 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
