SYNONYMS
CD8A, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, MAL, CD8, Leu2, p32, T-cell surface glycoprotein CD8 alpha chain isoform 1.
INTRODUCTION
CD8 protein is a glycoprotein that is located on the cell surface of cytotoxic T lymphocytes the interferes interactions between cells of the immune system. This protein is a coreceptor that helps detect antigens shown by the APC (antigen presenting cells) as part of the class I MHC proteins. It can be a homodimer build from 2 alpha chains orheterodimer build from alpha and beta chains.
DESCRIPTION
CD8A Human Recombinant produced in Baculovirus is a single, glycosylated, polypeptide chain containing 170 amino acids (22-182aa) and having a molecular mass of 18.7kDa.
CD8A is expressed with a 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
