C16ORF53

SYNONYMS
PAXIP1-associated protein 1, PTIP-associated protein 1, PA1, C16orf53, GAS.

INTRODUCTION
C16ORF53 is a component of a Set1-like multiprotein histone methyltransferase complex. C16ORF53 interacts with PAXIP1/PTIP; this interaction is direct and is necessary for the association with the rest of the PTIP complex. The C16ORF53 protein has a crucial role in maintaining genome stability, condensation of chromatin and progression through mitosis.

DESCRIPTION
C16ORF53 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 274 amino acids (1-254 a.a.) and having a molecular mass of 29.9kDa (Molecular weight on SDS-PAGE will appear higher).
C16ORF53 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

https://www.prospecbio.com/c16orf53_human