ASNA1

Attribute:

SKU : pro-1247

Recombinant Human arsA Arsenite Transporter, ATP-Binding, Homolog 1

Categories : Prospec , 

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SYNONYMS
ArsA Arsenite Transporter ATP-Binding Homolog 1 (Bacterial), Arsenical Pump-Driving ATPase, Transmembrane Domain Recognition Complex 40kDa, TRC40. ASNA-I, ATPase ASNA1, ARSA-I, GET3, Golgi To ER Traffic 3 Homolog, Arsenite-Stimulated ATPase, Transmembrane Domain Recognition Complex 40 KDa ATPase Subunit, HASNA-I, HARSA-I, ARSA, ARSA1, EC 3.6.3.16, EC 3.6.-.-.

INTRODUCTION
ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1) is a part of the arsA ATPase family. ASNA1 is the human homolog of the bacterial arsA gene. ArsA ATPase is the catalytic component of a multisubunit oxyanion pump In E.coli, which is in charge for resistance to arsenicals and antimonials. ASNA1 is also a main component of a transmembrane domain (TMD) recognition complex (TRC) which is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER).

DESCRIPTION
ASNA1 Human Recombinant produced in E. coli is a single polypeptide chain containing 371 amino acids (1-348) and having a molecular mass of 41.2 kDa. ASNA1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.


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