SYNONYMS
Anti-Muellerian hormone, AMH, Muellerian-inhibiting substance, MIS, MIF.
INTRODUCTION
Anti-Mullerian Hormone also known as AMH is a member of the TGF-beta family. AMH is a glycoprotein which is produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. AMH inhibits the growth of tumors derived from tissues of Muellerian duct origin. Moreover, AMH participates in Leydig cell differentiation and function in addition to follicular development in adult females.
DESCRIPTION
AMH Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain (a.a 452-560) containing 118 amino acids including a 9 a.a N-terminal His tag. The total molecular mass is 12.8kDa (calculated).
