SKU : pka-091
Recombinant Human Serine/Threonine Kinase 3
Categories : Prospec , 
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SYNONYMS
Serine/Threonine Kinase 3, Mammalian STE20-like protein kinase 2, MST-2, STE20-like kinase MST2, Serine/threonine-protein kinase Krs-1, MST2/N, MST2/C, KRS1,MST2.
INTRODUCTION
Serine/threonine-protein kinase 3 (), is a mammalian Ste20-related protein kinases most closely related to Drosophila Hippo, which is a major regulator of cell proliferation as well as survival in the course of development. STK3 is a serine/threonine kinase which functions early in a pheromone responsive signal transduction cascade in yeast. Furthermore, STK3 activates the human large tumor suppressor kinase Lats1. STK3 also modulates stress-induced cardiac hypertrophy.
DESCRIPTION
STK3 Human Recombinant produced in Sf9 Insect cell is a single, non-glycosylated polypeptide chain containing 331 amino acids (1-322aa.a) and having a molecular mass of 37.6kDa (Migrates at 40-57kDa on SDS-PAGE under reducing conditions).
STK3 is fused to a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.