SKU : pka-080
Recombinant Human Mitogen-Activated Protein Kinase 8
Categories : Prospec , 
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SYNONYMS
Mitogen-activated protein kinase 8, MAPK8, MAP kinase 8, MAPK 8, JNK-46, Stress-activated protein kinase 1c, SAPK1c, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, JNK1, PRKM8, SAPK1, SAPK1C, Mitogen-activated protein kinase 8 JNK beta 2, JNK, JNK1A2, JNK21B1/2.
INTRODUCTION
Mitogen-Activated Protein Kinase 8, also known as MAPK8, is a part of the MAP kinase family. MAP kinases an integration point for multiple biochemical signals which take part in a various cellular processes. MAPK8 is a protein coding gene which is also involved in UV radiation induced apoptosis that is associated to cytochrom c-mediated cell death pathway.
DESCRIPTION
MAPK8 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 450 amino acids (1-427a.a) and having a molecular mass of 50.5kDa.
MAPK8 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.