SKU : pka-079
Recombinant Human Mitogen-Activated Protein Kinase Kinase 6, sf9
Categories : Prospec ,
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SYNONYMS
Angiopoietin-1 receptor, Endothelial tyrosine kinase, HYK, STK1, Tunica interna endothelial cell kinase, Tyrosine kinase with Ig and EGF homology domains-2, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, mTIE2, p140 TEK, CD202b.
INTRODUCTION
Mitogen-Activated Protein Kinase 6 (MAP2K6) is a part of the dual specificity protein kinase family. MAP2K6 phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. MAP2K6 is a vital component of the MAP kinase signal transduction pathway. MAP2K6 takes part in various cellular processes such as stress induced cell cycle arrest and apoptosis.
DESCRIPTION
MAP2K6 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 340 amino acids (1-334 a.a.) and having a molecular mass of 38.3kDa (Migrates at 40-57kDa on SDS-PAGE under reducing conditions).
MAP2K6 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
