SKU : enz-134
Recombinant Human Tyrosyl-tRNA Synthetase
Categories : Prospec ,
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SYNONYMS
Tyrosyl-tRNA synthetase cytoplasmic, Tyrosyl--tRNA ligase, TyrRS, YARS, YRS, YTS, CMTDIC.
INTRODUCTION
Tyrosyl-tRNA synthetase (YARS) is a member of the class I tRNA synthetase family. YARS is a vital enzyme which catalyzes the aminoacylation of tRNATrp with tryptophan, a critical function of the cell’s protein synthesis machinery. Expression of YARS is highly stimulated in human cells by the addition of IFN-gamma.
DESCRIPTION
YARS produced in E.Coli is a single, non-glycosylated polypeptide chain containing 548 amino acids (1-528 a.a.) and having a molecular mass of 61.3kDa.
YARS is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
