SKU : enz-647
Recombinant Human Ubiquitin Conjugating Enzyme E2E1
Categories : Prospec , 
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SYNONYMS
Ubiquitin carrier protein E1, Ubiquitin-conjugating enzyme E2E 1 (homologous to yeast UBC4/5), Ubiquitin-protein ligase E1, UBCH6, EC 6.3.2.19.
INTRODUCTION
UBE2E1 belongs to the E2 ubiquitin-conjugating enzyme family. UBE2E1 accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. UBE2E1 catalyzes the covalent attachment of ISG15 to other proteins. UBE2E1 mediates the selective degradation of short-lived and abnormal proteins. In vitro, UBE2E1 also catalyzes 'Lys-48'-linked polyubiquitination.
DESCRIPTION
UBE2E1 Human Recombinant produced in E. coli is a single polypeptide chain containing 216 amino acids (1-193) and having a molecular mass of 23.8 kDa.
UBE2E1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.