SKU : enz-571
Recombinant Human Threonyl-tRNA Synthetase
Categories : Prospec ,
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SYNONYMS
Threonine--tRNA ligase, cytoplasmic, Threonyl-tRNA synthetase, ThrRS, TARS.
INTRODUCTION
Threonyl-tRNA synthetase, cytoplasmic (TARS) is a member of the class-II aminoacyl-tRNA synthetase family. The main role of TARS is in tRNA aminoacylation. The N-terminal domain of the TARS enzyme is responsible for the competition with the ribosome whereas the catalytic and the C-terminal domain are involved in binding the 2 anticodon arm-like structures in the operator.
DESCRIPTION
TARS Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 743 amino acids (1-723) and having a molecular mass of 85.6kDa.
TARS is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
