SKU : enz-409
Recombinant Human Estrogen Sulfotransferase
Categories : Prospec , 
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SYNONYMS
EST, STE, EST-1, MGC34459, SULT1E1, Estrogen sulfotransferase, Sulfotransferase estrogen-preferring.
INTRODUCTION
SULT1E1 catalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. Decreased SULT1E1 expression is linked with estrogen-dependent endometrial carcinomas. Altered cellular proliferation was detected in cells stably expressing SULT1E1.
DESCRIPTION
Recombinant Human SULT1E1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 302 amino acids (1-294 a.a.) and having a molecular mass of 36.1 kDa. SULT1E1 is fused to 6 amino acid His Tag at C-terminus and purified by conventional chromatography techniques.