PCOLCE, Sf9

SYNONYMS
Procollagen C-endopeptidase enhancer 1,  Procollagen COOH-terminal proteinase enhancer 1,  PCPE-1,  Procollagen C-proteinase enhancer 1,  Type 1 procollagen C-proteinase enhancer protein,  Type I procollagen COOH-terminal proteinase enhancer,  PCOLCE,  PCPE1,  Procollagen C-Endopeptidase Enhancer, Procollagen C-Proteinase, Enhancer 1, Procollagen, Type 1, COOH-Terminal Proteinase Enhancer, Type I Procollagen COOH-Terminal Proteinase Enhancer, Type 1 Procollagen C-Proteinase Enhancer Protein, Procollagen COOH-Terminal Proteinase Enhancer 1.

INTRODUCTION
Procollagen C-endopeptidase enhancer 1, also known as PCOLCE binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity. In addition, C-terminal processed part of PCPE (CT-PCPE) has a metalloproteinase inhibitory activity. Among the diseases which are associated with PCOLCE: bone fracture & oculopharyngeal muscular dystrophy.

DESCRIPTION
PCOLCE produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 433 amino acids (26-449 a.a.) and having a molecular mass of 46.6kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).

PCOLCE is expressed with an 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

https://www.prospecbio.com/pcolce_protein