SKU : enz-524
Recombinant Human Hypoxanthine-Guanine Phosphoribosyltransferase
Categories : Prospec ,
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SYNONYMS
Hypoxanthine-Guanine Phosphoribosyltransferase , EC 2.4.2.8, HGPRT, HGPRTase, HPRT, HPRT1.
INTRODUCTION
HPRT1 has a main part in the generation of purine nucleotides through the purine salvage pathway. HPRT1 primarily functions to salvage purines from degraded DNA to renewed purine synthesis. Therefore, it performs as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP.
DESCRIPTION
HPRT1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 238 amino acids (1-218 a.a.) and having a molecular mass of 26.7 kDa. The HPRT1 is fused to a 20 amino acids His-Tag at N-terminus and purified by proprietary chromatographic techniques.
