SYNONYMS
lacZ, beta-gal, b-gal, Acid beta-galactosidase, Lactase, Elastin receptor 1
INTRODUCTION
Beta-galactosidase or GLB1 is a B-galactosidase found in the lysosome. This enzyme hydrolyzes the finale B-galactose from the precursors ganglioside & keratin sulfate. GLB1 has a crucial part in the creation of elastogenesis (extracellular elastic fibers) and connective tissue development. This enzyme is similar to elastin-binding protein which is a key part in non-integrin cell surface receptor. In cells that extort elastin GLB1 is linked to tropoelastin intracellularly and act as recycling molecular chaperone.
DESCRIPTION
GLB1 Human produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 662 amino acids (24-677 a.a.) and having a molecular mass of 74.6 kDa.
GLB1 is fused to an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
