SKU : enz-530
Recombinant Human FK506 Binding Protein 14
Categories : Prospec ,
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SYNONYMS
FKBP22, FKBP-14, FK506 Binding Protein 14, FKBP14, EC=5.2.1.8, PPlase FKBP14, Peptidyl-prolyl cis-trans isomerase FKBP14, FLJ20731.
INTRODUCTION
FKBP14 enzyme accelerates the folding of proteins during protein synthesis. FKBP14 contains 2 EF-hand domains and one PPIase FKBP-type domain. Truncation of the amino-terminus of FKBP14 significantly decreases peptidyl prolyl cis-trans isomerase activity, therefore implicating that the PPIase FKBP-type domain must be located at the N-terminus.
DESCRIPTION
FKBP14 Recombinant E.coli produced in E.Coli is a single, non-glycosylated polypeptide chain containing 213 amino acids (20-211 a.a.) and having a molecular mass of 24.2 kDa. The FKBP14 is fused to 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
