SKU : enz-1073
Recombinant Mouse D-Dopachrome Tautomerase
Categories : Prospec ,
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SYNONYMS
D-dopachrome decarboxylase (EC:4.1.1.84), D-dopachrome tautomerase, Ddt.
INTRODUCTION
DDT is an enzyme that catayzes the tautomerization of D-dopachrome to give 5,6-dihydroxyindole (DHI). DDT is part of the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. DDT shares a homologous amino acid sequence (33% identical) with MIF and has similar tautomerase activity. DDT functions a proinflammatory cytokine.
DESCRIPTION
DDT Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids (1-118 a.a) and having a molecular mass of 15.5kDa. DDT is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
