SYNONYMS
Cytochrome P450, Family 2, Subfamily E, Polypeptide 1, CYP2E, Cytochrome P450, Subfamily IIE (Ethanol-Inducible), Polypeptide 1, 4-Nitrophenol 2-Hydroxylase, Cytochrome P450-J, P450C2E, CYPIIE1, Flavoprotein-Linked Monooxygenase, Microsomal Monooxygenase, Xenobiotic Monooxygenase, Cytochrome P450 2E1, EC 1.14.13.n7, EC 1.14.14.1, EC 1.14.13.-, P450-J, CPE1, Cytochrome P450 2E1.
INTRODUCTION
CYP2E1, also known as Cytochrome P450 2E1 belongs to the cytochrome P450 mixed-function oxidase system which is involved in the metabolism of xenobiotics in the body. While CYP2E1 is implicated in the oxidative metabolism of small range substrates, commonly small polar molecules, there are many significant drug interactions which are mediated by CYP2E1.
DESCRIPTION
CYP2E1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 488 amino acids (29-493 a.a) and having a molecular mass of 56.2kDa.CYP2E1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
