SKU : enz-902
Recombinant Human Carbonic Anhydrase XIII
Categories : Prospec , 
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SYNONYMS
Carbonic Anhydrase XIII, Carbonate Dehydratase XIII, EC 4.2.1.1, CA-XIII, Carbonic, Anhydrase 13, CAXIII.
INTRODUCTION
Carbonic Anhydrase XIII, also known as CA13 is a member of the alpha-carbonic anhydrase family, which catalyzes the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction which occurs relatively slowly in the absence of catalyst. Furthermore, the active site of nearly all carbonic anhydrases contains a zinc ion; they have been classified as metalloenzymes. At least five distinct CA families (?, ?, ?, ? and ?) have been found. These families have no significant a.a sequence resemblance and in just about all cases are considered to be an example of convergent evolution. The ?-CAs have been demonstrated in humans.
DESCRIPTION
CA13 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 285 amino acids (1-262a.a) and having a molecular mass of 31.8kDa.
CA13 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.