ALDH6A1

SYNONYMS
MMSADHA, MMSDH , Aldehyde Dehydrogenase 6 Family, Member A1, Methylmalonate-Semialdehyde Dehydrogenase [Acylating], Mitochondrial, Mitochondrial Acylating Methylmalonate-Semialdehyde Dehydrogenase, Malonate-Semialdehyde Dehydrogenase [Acylating], Aldehyde Dehydrogenase Family 6 Member A1, Malonate-Semialdehyde Dehydrogenase, EC 1.2.1.18, EC 1.2.1.27.

INTRODUCTION
ALDH6A1 or Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial is a mitochondrial methylmalonate semialdehyde dehydrogenase. ALDH6A1 participates in the valine and pyrimidine catabolic pathways. ALDH6A1 catalyzes the irreversible oxidative decarboxylation of malonate, propionyl-CoA and methylmalonate semialdehydes to acetyl. ALDH6A1 deficiency is distinguished by high levels of beta-alanine, 3-hydroxypropionic acid, and the two isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.

DESCRIPTION
ALDH6A1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 525 amino acids (34-535 a.a) and having a molecular mass of 56.8kDa. ALDH6A1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

https://www.prospecbio.com/aldh6a1_human