SKU : cyt-1063
Recombinant Human Prolactin, Pegylated
Categories : Prospec , 
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SYNONYMS
Mammotropin, Luteotropic hormone, Luteotropin, PRL.
INTRODUCTION
Prolactin is a neuroendocrine hormone synthesized primarily by the pituitary gland but also a variety of other cell types including the placenta, brain and uterus. Prolactin is secreted when eating, nursing, mating, estrogen treatment and during ovulation. Prolactin's primary role is to promote and maintain lactation but also plays a role in breast cancer development, regulation of reproductive function and immunoregulation.
DESCRIPTION
Prolactin Human Recombinant Pegylated produced in E.Coli is a single, non-glycosylated polypeptide chain containing 199 amino acids + an additional Ala at n-terminal. Pegylated Prolactin is mono-pegylated having a molecular mass of ~ 39 kDa, however under non-denaturing conditions it behaves as 220 kDa protein due to its increased hydrodynamic volume.
The Pegylated Prolactin protein is purified by proprietary chromatographic techniques.