mIL17RB

SYNONYMS
Il17rb, Evi27, IL-17ER, IL-17Rh1, Il17br, IL17RH1, IL-17 receptor B, IL-17RB, Interleukin-17 receptor B.


INTRODUCTION
IL17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. Interleukin-17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

DESCRIPTION
IL17RB produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 511 amino acids (18-286 a.a.) and having a molecular mass of 57.1kDa (Molecular size on SDS-PAGE will appear at approximately 57-70kDa). IL17RB is expressed with an 242 amino acid hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques.

https://www.prospecbio.com/il17rb_mouse