SYNONYMS
Leukocyte IFN, B cell IFN, Type I IFN, IFNA2, IFN-a 2a.
INTRODUCTION
IFN-alpha is produced by macrophages and has antiviral activities. IFN stimulates the production of two enzymes: protein kinase and an oligoadenylate synthetase.
DESCRIPTION
IFN Alpha Human 2a Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19241 Dalton. The difference between IFNA2A and IFNA2B is in the amino acid present at position 23. IFN-alpha 2a has a lysine at that position 23 while IFN-alpha 2b has arginine.
The IFNA2A gene was obtained from human leukocytes.
The IFNA2A is purified by proprietary chromatographic techniques.
