FGF2, 293 Cells

SYNONYMS
Prostatropin, HBGH-2, HBGF-2, FGF-2, FGF-b.


INTRODUCTION
Basic fibroblast growth factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.


DESCRIPTION
FGF-2 Human Recombinant Thermostable produced in HEK cells is a non-glycosylated monomer, containing 154 amino acids and having a total molecular weight of 17kDa.
FGF-2 Thermostable is a protein engineered FGF2 in order to enhance its thermostability without modifying its biological function.
The FGF-b is purified by proprietary chromatographic techniques.

https://www.prospecbio.com/fgf_2_human_hek