SKU : A-415-10
Categories : 1. Chemical and Reagents ,  Gold Biotechnology (USA) , 
Brand : Gold Biotechnology (USA)
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Acalabrutinib (ACP-196) is an irreversible inhibitor of Bruton’s tyrosine kinase (BTK), which is responsible for the maturation of B-cells. Its high selectivity to bind the residue Cys481 in the active site of BTK is a sought after feature for oncology research. Studies on mice and human cells demonstrate the high affinity of ACP-196 and its low affinity toward similar proteins in T-cell maturation.
Product Specifications
Acalabrutinib
ACP-196
Formula: C26H23N7O2
MW: 465.51 g/mol
Storage/Handling: Store desiccated at -20°C.
PubChem Chemical ID: 71226662
Product Specifications
Catalog ID | A-415 |
---|---|
CAS # | 1420477-60-6 |
MW | 465.51 g/mol |